Prabhupāda: Material life means everyone is trying to become victorious in the struggle of existence without God consciousness. That is our material disease. Kṛṣṇa-boliya jīva bhoga vāñchā kare (Prema-vivarta). We may revolt. That independence we have got, little independence, and we can misuse it, that "Why shall I serve Kṛṣṇa? Let me serve myself." "Let me serve myself' means "Let me serve my different propensities—kāma, krodha, lobha, moha, mātsarya," like that. My independence means "I will not serve God; I will serve my lusty desires." You cannot become independent. This is a concoction only, that "I will not serve Kṛṣṇa." But you have to serve. What is that? "Then I serve my lusty desires." Indriya-tṛpti, indriya-tṛpti. Yad indriya-prītaye. Simply to satisfy... Kṛṣṇa consciousness means there is no such thing as indriya-tṛpti, or sense gratification. Everything for the satisfaction of the Supreme Lord: hṛṣīkeṇa hṛṣīkeśa-sevanaṁ bhaktir ucyate (CC Madhya 19.170). Hṛṣīka means the indriya, or the senses. That is stated here also, manasaś cendriyāṇāṁ ca bhūtānāṁ mahatām api, that different types of indriya for sense gratification, we develop. This is the creation, every one of us developing, and it is become complicated with so many other desires. Each life is full of desires. Therefore in the Guru-stotra in the morning we recite, ār nā koriho mane āśā. Is it not? What is that?
Devotee: Ār nā koriho mane āśā.
Prabhupāda: Ār nā koriho mane āśā. So that is required. Guru-mukha-padma-vākya... Eh?
Devotee: Cittete koriyā aikya.
Prabhupāda: Cittete koriyā aikya, ār nā koriho mane āśā. That is liberation. Otherwise, we shall be implicated. And what guru says? Guru says the same thing as Kṛṣṇa says. That is guru. Kṛṣṇa says, sarva-dharmān parityajya mām ekaṁ śaraṇaṁ vraja (BG 18.66). Kṛṣṇa also... Guru also says the same thing. That is guru's business, that "You surrender to Kṛṣṇa and fully be engaged in Kṛṣṇa's service." So therefore Narottama dāsa Ṭhākura advises, "Take this very seriously." Ār nā koriho mane āśā: "No more. Stop any other desires." Then your life is successful. Ār nā koriho mane āśā.
bahu-śākhā hy anantāś ca
Buddhayo 'vyavasāyinām. Vyavasāyātmikā, niścayātmikā. "Now, my life will be successful when I accept very seriously the instruction given by Kṛṣṇa and it is delivered to me through the transparent via media of guru. Then it will be successful."
(Srila Prabhupada Lecture, January 1, 1975, Bombay)